In seismic response analysis of building structures, the input ground accelerations have considerable effect on the nonlinear response characteristics of structures. The characteristics of soil and the locality of the site where those ground motions were recorded affect on the contents of earthquake waves. Therefore, it is difficult to select appropriate input ground motions for seismic response analysis. This study describes a generation of artificial earthquake wave compatible with seismic design spectrum, and also evaluates the nonlinear response spectra by the simulated earthquake motions. The artificial earthquake wave are generated according to the previously recorded earthquake waves in past earthquake events. The artificial wave have identical phase angles to the recorded earthquake wave, and their overall response spectra are compatible with seismic design spectrum with 5% critical viscous damping. Each simulated earthquake wave has a identical phase angles to the original recorded ground acceleration, and match to design spectra in the range of period from 0.02 to 10.0 seconds. The seismic response analysis is performed to examine the nonlinear response characteristics of SDOF system subjected to the simulated earthquake waves. It was concluded that the artificial earthquake waves simulated in this paper are applicable as input ground motions for a seismic response analysis of building structures.