본 연구는 새로이 개발된 근관세정제 (MTAD)가 근관 충전이 이루어지고 난 치근단 누출에 미치는 영향을 평가해 보고자 하였다. 일반적인 방법의 근관 성형과 세정 그리고 충전을 시행하는데 있어 실험군 들에서는 NaOCl만, NaOCl과 EDTA, NaOCl과 MTAD를 사용하였고 10일 동안 표준전극과 시편 근관 내에 위치시킨 실험전극 사이의 전기저항을 측정하여 시간에 따른 치근단 누출의 변화를 비교 평가하였다. 실험결과 측정 시간 30분에서 7일 사이에서 smear layer 제거한 군들 (Group 4와 5)에서 제거하지 않은 군(Group 3)에서 보다 적은 치근단 누출을 보였지만 통계학적인 유의성있는 차이를 나타내지는 않았다 실험군들 사이에서 모든 시간 대에 걸쳐 치근단 누출의 유의성 있는 차이를 관찰할 수 없었다.
The purpose of this study was to evaluate the effect of newly developed endodontic root canal cleanser (MTAD) on the apical leakage of obturated root canal using an electrochemical method. Canals of 60 extracted single-rooted human teeth were prepared by using a crown-down technique with rotary nickel-titanium files. In Group 1 (positive control group) and 2 (negative centre) group), 5.25% NaOCl was used as a canal irrigant and no canal wall treatment was done. In group 3 only 5.25% NaOCl were used as canal irrigant, canal wall treatment and final rinse. In group 4, specimens were irrigated with 5.25% NaOCl, treated with 5 ml of 17% EDTA for 5 minutes and final rinsed with 5.25% NaOCl Specimens of group 5 were irrigated with 1 3% NaOCl and treated with 5 ml of MTAD for 5 minutes. All root canals are dried with paper points and obtuated with gutta-percha and AH plus as a sealer using a continuous wave of condensation technique except in the group 1. The electrical resistance between the standard and experimental electrodes in canals was measured over a period of 10 days. Rising of apical leakage with time was observed for all the groups. Group 4 and 5 showed lower apical leakage than group 3 but differences between the group 3, 4 and 5 were no statistical significance at any measurement time.
