This study concerns the performance of condensation heat transfer in plain and grooved thermosyphons. Distilled water, methanol, ethanol have been used as the working fluids. In the present work, a copper tube of the length of 1200mm and 14.28mm of inside diameter is used as the container of the thermosyphon. Each of the evaporator and the condenser section has a length of 550mm, while the remaining part of the thermosyphon tube is adiabatic section. A study was carried out with the characteristics of heat transfer of the thermosyphon 50, 60, 70, 80, 90 helical grooves in which boiling and condensation occur. The liquid filling as the ratio of working fluid volume to total volume of thermosyphon, the kinds of working fluid, the inclination angle, grooves and operating temperature have been used as the experimental parameters. The experimental results show that the number of grooves, the amount of the working fluid, the kind of working fluid, angle of inclination angle are very important factors for the operation of thermosyphon. The maximum heat transfer was obtained when the liquid fill was about 20 to 25 % of the thermosyphon volume. The relatively high rates of heat transfer have been achieved in the thermosyphon with grooves. The helical grooved thermosyphon having 70 to 80 grooves in water, 60 to 70 grooves in methanol and 70 to 80 grooves in ethanol shows the best heat transfer coefficient in both condensation.