This paper describes the design and behaviour of cold-formed stainless steel slender circular hollow section columns. The columns were compressed between fixed ends at different column lengths. The investigation focused on large diameter-to-plate thickness (D/t) ratio ranged from 100 to 200. An accurate finite element model has been developed. The initial local and overall geometric imperfections have been included in the finite element model. The material nonlinearity of the cold-formed stainless steel sections was incorporated in the model. The column strengths, load-shortening curves as well as failure modes were predicted using the finite element model. The nonlinear finite element model was verified against test results. An extensive parametric study was carried out to study the effects of cross-section geometries on the strength and behaviour of stainless steel slender circular hollow section columns with large D/t ratio. The column strengths predicted from the parametric study were compared with the design strengths calculated using the American Specification, Australian/New Zealand Standard and European Code for cold-formed stainless steel structures. It is shown that the design strengths obtained using the Australian/New Zealand and European specifications are generally unconservative for the cold-formed stainless steel slender circular hollow section columns, while the American Specification is generally quite conservative. Therefore, design equation was proposed in this study.