In recent years, the demands of the aspheric glass lenses increase since it is difficult to obtain the desirable performance in the plastic lens. Glass lens is manufactured by the forming with high precision mold core. This paper presents the analysis of optimal grinding condition of tungsten carbide(WC, Co 0.5%) using design of experiments(DOE). The process parameters are turbin spindle, work spindle, feedrate and depth of cut. The experiments results are evaluated by MINITAB software.