Purpose: This study was to identify affecting factors on job satisfaction, nursing professional attitudes of new nurses according to transformational leadership of preceptors. Method: The subjects were 101 new nurses who were working for the 4 of university hospitals in Seoul, Daejeon and Kyong Ki. This study was conducted from Aug to Oct 2005. The data was collected by questionnaires and were analyzed using descriptive statistics, pearson correlation coefficient, stepwise multiple regression. Result: Transformational leadership of preceptors were significantly correlated between Job satisfaction, nursing professional attitudes of the new nurses. The stepwise multiple regression analysis for job satisfaction, nursing professional attitudes revealed that the most powerful predictor was charisma. Conclusion: The findings indicated that the transformational leadership of preceptors is important for improving job satisfaction, nursing professional attitudes of the new nurses. Therefore it may be necessary further to develop of the leadership training program for effective preceptorship.