The factor of air pollution in a large industrial city is not only manufactories but also, activities related to trucks. Sihwa National Industrial Complex is located in Siheung City; due to the industries, more diverse activities related to trucks occur in Siheung City than other cities. In particular, the new residential area in Siheung City is close to the industrial complex; so, the damage of this residential area is expected that it would be more serious and vulnerable than other areas. The aim of this study is to analyze influence of the air pollution by a truck in Siheung City. ISCST3 Model and Arc View program were used for this study and Siheung City was divided into 1,000 meter by 1,000 meter grid to analyze. Furthermore, this study suggested two reduction controls of air pollution in Siheung City, and analyzed the results from these reduction managements. The results of the present condition showed that residences located in north of Sihwa Industrial Complex are influenced by air pollution material. Furthermore, air pollution by trucks has affected on the residents which is near the road in Siheung City. Therefore, this study suggested two reduction controls by the Traffic System Management. The first alternative plan is setting the truck traffic limitation zone in the road that is located in south of resident areas and many trucks traffic. Next, the second alternative plan is setting freight truck way on the most traffic road to enter the industrial complex. The reduction effect of the first alternative is good on the residential area. And, the second alternate about freight truck way is divided passenger cars into trucks. Therefore, there are increase of average speed and decrease of average concentration, and spatial reduction effects found in wide areas.