Purpose: This study was to explore the degree of quality of life (QOL) in hospice volunteers and identify related factors Methods: A total of 243 subjects was recruited from eight hospitals of the Catholic University in Korea. Research tool used to measure QOL was questionnaires developed by You-Ja, Ro in 1988. The data obtained was analyzed using the SAS program to compute a t-test, ANOVA, and Stepwise multiple regression. Results: The mean score of QOL was $3.65{pm}0.39$. The QOL was significantly increased with perceived health status, satisfaction to the hospice volunteer activity, family response on volunteer activity, qualification as a hospice volunteer, and needs of education. Among six domains of QOL, self-esteem had the highest score. Conclusions: It would be necessary for hospice volunteers to provide an program considered health status, satisfaction to the hospice volunteer activity, family response on their activity, qualification as a hospice volunteer, and needs of education to increase their QOL.