The purpose of this study was to identify the relationship between lifestyles and clothing shopping orientation. A questionnaire was developed to measure the lifestyle and shopping orientation of Chinese female college students. The questionnaire was distributed and collected from 217 college female students in China. The data was analyzed by mean, standard deviation, factor analysis, reliability test, MANOVA and ANOVA by SPSS package. The lifestyles of the respondents were classified into four types such as Open-mindedness, Accomplishment, Sociability, and Activities. And shopping orientation was classified into five types such as Recreational shopping, Speediness, Economic shopping, Shop and brand royalty, and Self-confidence. The result of this study were as follows; Consumers of open-minded lifestyle tended to economic and self-confident shopping. The higher accomplishment was, the higher speediness and economic shopping were. Consumers of sociable lifestyle tended to recreational, speediness, and self-confidence. The higher activities was, the higher economic shopping was. The shop and brand royalty was not shown to have the significant differences according to all of lifestyle groups. It is the factor that lifestyle were important in the clothing market segmentation of Chinese female college students