The concept of reliability has been applied to the topology optimization based on a reliability index approach or a performance measure approach. Since these approaches, called double-loop single vector approach, require the nested optimization problem to obtain the most probable point in the probabilistic design domain, the time for the entire process makes the practical use infeasible. In this work, new reliability-based topology optimization method is proposed by utilizing single-loop single-vector approach, which approximates searching the most probable point analytically, to reduce the time cost. The results of design examples show that the proposed method provides efficiency curtailing the time for the optimization process and accuracy satisfying the specified reliability.