In this paper, a new interference-free Home CDMA-PLC(Code Division Multiple Access-Power Line Communication) system based on the binary ZCD(Zero Correlation Duration) spreading code is proposed as a key solution to overcome the previous problems. Binary ZCD spreading code sets with enlarged family sizes are generated by carrying out a chip-shift operation of the preferred pairs. The properties or the proposed ZCD-PLC systems are effective for MPI(Multi-Path Interference) and MAI (Multiple Access Interference) cancellation in the CDMA-PLC systems. By BER performance simulation, we certified the availability of proposed ZCD-CDMA-PLC system.