This paper proposes an adaptive inter-agent communication protocol to considerably reduce the amount of agent location information maintained by each service node and the message delivery time while avoiding the dependency of the home node of a mobile agent. To satisfy this goal, the protocol enables each mobile agent to autonomously leave its location information only on some few of its visiting nodes. Also, it may significantly reduce the agent cache updating frequency of each service node by keeping the identifier of the location manager of each agent in the smart agent location cache of the node. Simulation results show that the proposed protocol reduces about $76%{sim}80%$ of message delivery overhead and about $76%{sim}79%$ of the amount of agent location information each service node should maintain compared with the traditional one.