Bristles for the prosthetic and periodontally involved patients are investigated based on previous studies. Specifically, the ideal location and dimensions of bristles for the patients who were installed with fixed prostheses and severely involved periodontitis were investigated. 3D (Three-Dimensional) scanner was used to develop 3D visual models of bristles and teeth. These models were used for designing the ideal bristles. In the design, the interproximal area of dental arch and bristle must be maximized and the standard teeth may have to be chosen from many gypsum molds. During the design process the factors that influence plaque removal by the bristle were considered.