A portable ECG sensor module and monitoring system which has the powerline noise reduction and the baseline wander removal is proposed. A small-szie ECG sensor H/W module with the 8-bits microprocessor is implemented. The ECG waveform can be inspected anytime with PDA in real time, and transmitted to the PC through wireless LAN. Portable ECG system can offer the environment that give the lasting medical service to the elderly and the long-time hospitalized patients at the wanted place, and the system can be attached to the chair, wheel chair, treadmill, elderly walker and used to monitor the health condition of man