The Syndrome Differentiation(辨證) means to make diagnosises and to classify symptoms based oriental medicine theory. Questionnaires and clinical decision support system would assist the doctor checks up symptoms of a patient. We analyze about domestic and foreign patents and papers of these diagnosis tools and catch the trend. In patents, the system examines by telemedicine and offers medical information and prescriptions to patient. Papers was itemized fields ; theory, methods of analysis, clinical application, questionnaire, clinical decision support system. The results of this research can be applied to develop the high-quality tool to support syndrome differentiation.