Bioinformatics and medical informatics have moved to make its knowledge more systematically and computationally using ontology. These ontologies help querying ring and analyzing data and used to develop application in biomedical. However, no research about ontology of oriental medical exists. Thus, to maximize the power of transitional knowledge, it is necessary to construct the ontology for oriental medical. This paper compares the ontologies of bio and medic by an objective point of view to guide the construction of oriental medic ontologies.