This paper described design method to minimize the crosstalk effect of multiaxis thrust measurement stand which can measure the thrust vector control performance of Solid Rocket Motor. This paper presents a theoretical solution for predicting the magnitude of crosstalk and calculates design sensitivity. The results indicate that the most important parameter of crosstalk is the displacement of flexure-loadcell-flexure assembly. And shape, dimension and mechanical properties of flexure and loadcell can also influence the magnitude of crosstalk.