The concept of slope rotatability introduced by Hader and Park(1978) is available when we are interested in the difference of the responses. Since there can be constraints on the factor levels in mixture experiments, there arises a need for adaptation of the concept of slope rotatability and the measure to assess it. In this article, measures of slope rotatability in mixture experiments are proposed to quantify the amount of slope rotatability for a given design. Measures for a restricted region design as well as for an unrestricted region design are presented. Then, the designs having different optimalities are compared with respect to these measures by some examples.