Purpose: The purpose of this study was to report the clinical effectiveness of Traditional Korean Treatment on infertility patients with endometriosis. Methods: The patient in this case was 32 years-old female. The chief complains were lower abdominal pain, dysmenorrhea, infertility with endometriosis. She was treated by Traditional Korean Medicine, acupuncture and retention enema therapy. So the symptom of she complained was improved. Results: After the retetion enema therapy and Traditional Korean Medicine, the lower abdominal pain and dysmenorrhea of endometriosis was improved. And she was pregnant and delivered. Conclusion: This case study shows that the retetion enema and Traditional korean therapy were effective in treating endometriosis and fertility. So we make more studis about this disease, it will bring the high satisfaction of patient and the improvement of treatment rate.