Stream flow and water quality were measured and analyzed with respect to flow-weighted mean concentrations (FWMCs) of 21 rainfall events from a forested watershed (Forest Research Watershed: FRW) and two mixed watersheds of agriculture and forest (YuPo-Ri Watershed: YPW and WolGog-ri Watershed: WGW) located in the middle of the North Han River basin. The monitoring of each watershed was one year and conducted between 2004 and 2006. YPW showed more intensive agricultural practices than WGW where traditional practices were common. The average of the 21 FWMCs were in the order of YPF>WGW>FRW and were significantly different from each other at the level of 0.05. It was shown that the land use with intensive agricultural practices produced and discharged more NPS pollutants than that with traditional practices and forest. Specially, SS concentrations from the mixed watersheds were significantly higher than those from FRW. Influencing factors on runoff were analyzed rainfall and watershed area. And rainfall intensity was greater impact on runoff than daily rainfall. Measured water quality indices were shown positive correlations among them in general. However, no significant correlation was shown between COD and nutrients(T-N and T-P).