Refrigeration and air-conditioning equipments are indispensable products in this civilized society. However, discharged refrigerants used in the equipments and exhausted carbon dioxide to drive the refrigeration and air-conditioning equipments are related to serious environmental problems and energy problems. Especially, the destroyed ozonosphere by the discharged refrigerants and the increased normal temperature by carbon dioxide and fluorocarbon refrigerants (green house gases) are sounded as serious global problems. For alleviating these problems, environmental-friendly refrigeration and air-conditioning equipments must be developed and will spread soon. To develop new equipment, a suitable refrigerant for each usage must be presented. In this paper, the current state of refrigerants was introduced. And, thermophysical properties of the refrigerants were introduced briefly. From the properties, the refrigerants and refrigeration cycles are promising to be used in the future, were proposed