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개의 피부 감염창 치유에 대한 녹차 추출물의 국소도포 효과
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  • 개의 피부 감염창 치유에 대한 녹차 추출물의 국소도포 효과
  • Effect of Green Tea Extract on Healing of Contaminated Wound in Dogs
저자명
김보람,정종태,박현정,윤영민,이경갑,강태영,김재훈,배종희,이주명,Kim. Bo-Ram,Cheong. Jong-Tae,Park. Hyun-Jeong,Yun. Young-Min,Lee. Kyoung-Kap,Kang. Tae-Young
간행물명
Journal of veterinary clinics
권/호정보
2007년|24권 4호|pp.550-556 (7 pages)
발행정보
한국임상수의학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

The purpose of this study is to assess healing effect of the green tea on Staphylococcus contaminated wound. On the back of 7 dogs, 6 full-thickness skin wounds($2cm{ imes}2cm$) were made and Staphylococcus intermedius was inoculated. Each wound was applied with the 2%(experimental group I), 1%(experimental group II) extract of green tea and normal saline(control group I) after inoculation. The wound contraction rate of the experimental group I and II was higher than that of the control group in entire period. And from the $6^{th};to;22^{nd}$ day, the wound contraction rate of the experimental group I and II was significantly higher than that of the control group(p<0.05). The occupation rate of wound healing in the experimental group I was higher than that of the control group from $0;to;9^{th}$ day except from $1^{st};to;2^{nd}$ day and also higher than that of the experimental group II from $0;to;3^{rd}$ day except from $1^{st};to;2^{nd}$ day. And the occupation rate of wound healing in the experimental group II was higher than that of the control group from $1^{st};to;8^{th}$ day except from $2^{nd};to;3^{rd}$ day. According to concentration of green tea extract increased, the wound contracted more vigorously in earlier period. The tensile strength of the experimental group I and II was significantly higher than that of the control group(p<0.05). And that of the experimental group I was also higher than in the experimental group II(p<0.05). The number of S. intermedius in the experimental group I and II was decreased more rapidly than that of the control group. From the $4^{th}$ to the $11^{th}$ day, the number of S. intermedius in the experimental group I was significantly lower than that of the experimental group II and the control group. And from the $4^{th}$ to the $7^{th}$ day, the number of S. intermedius in the experimental group was significantly lower than that of the control group. The histopathological findings of the experimental group I and II were similar to those of the control group on the $1^{st};and;4^{th}$ day. On $14^{th}$ day, reepithelialization was completed in the experimental group I and II except the control group. Higher wound contraction rate, better bacteriocidal action, higher tensile strength and better histopathological findings were observed in the experimental group I and II than in the control group. These results suggest that the topical application of green tea extract can promote contaminated wound healing in dogs.