Earthquake time-history analyses have been carried out for a buried gas pipeline of X65 which is of popular use in Korea. Parameters included are shape of a buried gas pipeline, soil characteristics, single and multiple earthquake input ground motions and burial depths. Predicted response of strain and relative displacement are then compared with allowable strain and displacement capacity calculated by Guidelines for the Seismic Design of Buried Gas Pipelines, KOGAS. Comparative studies show that strains are in general affected by the burial depths together with change of soil conditions. Regarding the relative displacement, while axial relative displacement is not influenced by the burial depths, transverse relative displacement is affected by both burial depths as well as soil conditions. In all, the current study is encouraged to give a useful information for healthy earthquake evaluation of a buried pipeline.