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가토 하악골 골신장 후 맥동전자기장이 조기 골경화에 미치는 효과에 대한 연구
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  • 가토 하악골 골신장 후 맥동전자기장이 조기 골경화에 미치는 효과에 대한 연구
저자명
황경균,조태형,송윤미,김도균,한성희,김인숙,황순정,Hwang. Kyung-Kyun,Cho. Tae-Hyung,Song. Yun-Mi,Kim. Do-Kyun,Han. Sung-Hee,Kim. In-Sook,Hwang. Soon-Ju
간행물명
대한악안면성형재건외과학회지
권/호정보
2007년|29권 2호|pp.123-131 (9 pages)
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대한악안면성형재건외과학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Introduction: Distraction osteogenesis is widely used as for bone lengthening in patients with maxillofacial deformity and alveolar bone atrophy. One of the major problems in distraction osteogenesis is long consolidation period for 2-3 months, in which the devices have to be fixed on the bone to prevent relapse. It results in scar formation on the face, disturbance of mastication and speech. This study was performed to evaluate the stimulating effect of pulsed electromagnetic field on the early bone consolidation in distraction osteogenesis. Materials and methods: Total 10 rabbit were used (5 for control group, 5 for experimental group). A vertical osteotomy in the mandibular body was performed and the distraction device was fixed. After 5 days distraction was done 1mm per a day for 7 days. A pulsed electromagnetic field (38 Gauss, 60 Hz) was applied for 8 hours per day and it continued for 5 days immediately after distraction in the experimental group. Both groups were sacrificed after 2 weeks. Histological specimens with H&E and Masson Trichrome staining were made and histomorphometrically analysed with image analyser. Results: The device for distraction osteogenesis was displaced in one animal for each group, therefore, only four animals in both groups were evaluated. In both groups, a new bone formation was observed in the distracted area after 2 weeks. The bone formation was enhanced in the experimental groups ($31.76{pm}8.68%$) compared with control group ($9.94{pm}3.23%$), its difference was statistically significant (p<0.001). Conclusion: This study suggests that electrical stimulation with electromagnectic field may be effective in the early bone formation after distraction osteogenesis. Further studies with large number of animals are needed before clinical application.