Through lessons in recent earthquakes, the bridge engineering community recognizes the need for new seismic design methodologies based on the inelastic structural performance of RC bridge structures. This study represents results of performance-based fragility analysis of reinforced concrete (RC) bridge. Monte carlo simulation is performed to study nonlinear dynamic responses of RC bridge. Two-parameter log-normal distribution function is used to represent the fragility curves. These two-parameters, referred to as fragility parameters, are estimated by the traditional maximum likelihood procedure, which is treated each event of RC bridge pier damage as a realization of Bernoulli experiment. In order to formulate the fragility curves, five different damage states are described by two practical factors: the displacement and curvature ductility, which are mostly influencing on the seismic behavior of RC bridge piers. Five damage states are quantitatively assessed in terms of these seismic ductilities on the basis of numerous experimental results of RC bridge piers. Thereby, the performance-based fragility curves of RC bridge pier are provided in this paper. This approach can be used in constructing the fragility curves of various bridge structures and be applied to construct the seismic hazard map.