Purpose : To investigate the effectiveness of local vibration and interferential therapy for patient with acute low back pain. Methods : A randomized trial designed to compare interferential therapy and local vibration therapy for acute low back pain in primary care setting Results : A total of 60 patients were recruited. The two treatment groups had similar demographic and clinical baseline characteristics. The mean VAS scores before treatment was 8.290 for interferental therapy group and 8.572 for local vibration therapy groups. After treatment, this VAS score had dropped to 4.812(interferental therapy group, at 7 days), and 4.945(local vibration group, at 7 days). Conclusion : This study shows a progressive fall in visual analog scale scores in patients with acute low back pain treated with either interferential therapy and local vibration therapy. There was some difference in the improvement between the two groups at 1 to 4 days, VAS score of vibration therapy groups was low better than interferential therapy groups.