This paper deals with a fault detection system design for nonlinear systems with uncertain time varying parameters modelled as a T-S fuzzy system. A coprime factorization for T-S fuzzy systems is defined and a residual generator is designed using a left coprime factor. A fault detection criteria derived from the residual generator is also suggested. In order to demonstrate the efficacy of the suggested method, the fault defection method is applied to an inverted pendulum system and computer simulations are performed.