Herbal medicine has been traditional used for prevention and treatment of treatment of disease, because herbal medicine has few side effects in the human body. Anti-medicines such as antimicrobial medicine and anti-cancer medicine, which contains herbal medicine, are being studied vigorously by researchers. The effects of Geum Japonicum Thumb are restorative, blood circulation and detoxification. It also treats hematemesis, menstruation and furunculus. The ingredients of Geum Japonicum Thumb include geoside and tannin. The study measured antioxidative activation and antifungal activation by using Geum Japonicum Thumb water and methanol extract. The crude extract, which was used for this study, was Korean herbal medicine and the results are as follows. As Geum Japonicum Thumb extracts get stronger, the antioxidative activation tended to increase. The antioxidative activation hit its peak when the density of methanol extract was 120ug/ml. The experiment showed that a 1.0mm clear zone appeared when the density of the Geum Japonicum Thumb methanol extracts were 1000ug/ml in the Staphylococcus epidermidis and 1.1mm clear zone at Pseudomonas aeruginosa. The results of this study concludes that the antioxidative activation is lubricated in the Geum Japonicum Thumb extracts. In addition, the antifungal activation occurred in the fungus of the Staphylococcus epidermidis and the Pseudomonas aeruginosa.