Yeon Ju Hwan (蓮珠丸) is a Chinese patent medicine which has been used for improvement of blood circulation and thrombolysis in Korea. It consists of 28 kinds of powdered crude drugs. For the identification of individual ingredients in such powdery mixtures, microscopic method may advantageously be used, as it requires only small amount of specimens. And also it is considered a technique of choice since it takes only minimum time and requires a simple process. In this paper, the effectiveness of this method is exemplified by the identification of the ingredients in Yeon Ju Hwan, which contains 28 powdered crude drug ingredients.