The purpose of this study is to suggest hospital clothing design which reflects ubiquitous info-communications technology as changing hospital environment in the information-oriented era of the 21st century. The methods of this study are documentary research of previous studies, observation research and deep interviews. Seoul national university hospital is selected as a target of observation for this study. Doctors, nurses, pharmacists, and patients who are the representative jobs in the hospital are interviewed from on July, 13, 2006 to on August, 1, 2006. According to observation research, the computers, OCR, and PACS are applied from registration to dosage through all courses of diagnosis. However, the most inconvenient problems to patients are the location of medical offices and confusion of reservation. Also, the needs and inconveniences of doctors, nurses, pharmacists, and patients are almost solved by using RFID technology as a result of deep interviews. They prefer wearing devices as an accessory to wearing devices as a clothing directly. In conclusion, suggested UFC design for hospital clothing with info-communications technology promotes efficiency, accuracy, convenience of work to medical personnel in changing hospital environment as the flow of the information-oriented era of the 21st century.