Based on the composite finite element simulation and a series of hydrostatic pressure and burst tests, autofrettage effects on strength and deformation of fiber reinforced pressure vessel with metallic liners have been studied in the paper (autofrettage: during the course of one pressure taking effect, the increasing internal stress in metallic liner can surpass the yielding point and the plastic deformation will happen, which result in that when there is no internal pressure, there are press stress in liner while tensile stress in fiber lamination). By making use of a composite finite element Ansys code and a series of experiments, the autofrettage pressure is determined in order to make the aluminium liner be totally in elastic state, under given hydrostatic test pressure. The stress intensity factors of the longitudinal crack in aluminum liner end under internal pressure and thermal loads have been computed and analyzed before and after the autofrettage processing. Through numerical calculation and experiment investigations, it is found that a correct choice for autofrettage pressure can improve the gas-tightness and fatigue strength of FRP vessel.