A rational three-dimensional nonlinear finite element model is described and implemented for evaluating the behavior of high strength concrete slabs under transverse load. The concrete was idealized by using twenty-nodded isoparametric brick elements with embedded reinforcements. The concrete material modeling allows for normal (NSC) and high strength concrete (HSC), which was calibrated based on experimental data. The behavior of concrete in compression is simulated by an elastoplastic work-hardening model, and in tension a suitable post-cracking model based on tension stiffening and shear retention models are employed. The nonlinear equations have been solved using the incremental iterative technique based on the modified Newton-Raphson method. The FE formulation and material modeling is implemented into a finite element code in order to carry out the numerical study and to predict the behavior up to ultimate conditions of various slabs under transverse loads. The validity of the theoretical formulations and the program used was verified through comparison with available experimental data, and the agreement has proven to be very good. A parametric study has been also carried out to investigate the influence of different material and geometric properties on the behavior of HSC slabs. Influencing factors, such as concrete strength, steel ratio, aspect ratio, and support conditions on the load-deflection characteristics, concrete and steel stresses and strains were investigated.