A flexibility-based distributed computing strategy (DCS) for structural health monitoring (SHM) has recently been proposed which is suitable for implementation on a network of densely distributed smart sensors. This approach uses a hierarchical strategy in which adjacent smart sensors are grouped together to form sensor communities. A flexibility-based damage detection method is employed to evaluate the condition of the local elements within the communities by utilizing only locally measured information. The damage detection results in these communities are then communicated with the surrounding communities and sent back to a central station. Structural health monitoring can be done without relying on central data acquisition and processing. The main purpose of this paper is to experimentally verify this flexibility-based DCS approach using wired sensors; such verification is essential prior to implementation on a smart sensor platform. The damage locating vector method that forms foundation of the DCS approach is briefly reviewed, followed by an overview of the DCS approach. This flexibility-based approach is then experimentally verified employing a 5.6 m long three-dimensional truss structure. To simulate damage in the structure, the original truss members are replaced by ones with a reduced cross section. Both single and multiple damage scenarios are studied. Experimental results show that the DCS approach can successfully detect the damage at local elements using only locally measured information.