Treatment options for anastomotic recurrence occurring after Ivor Lewis operation are limited. Reoperation for resection can be technically challenging and several reports suggest a potential survival benefit from re-resection. Specific care must be taken to avoid compromise of the previously transposed conduit to not endanger its vascular supply and the recurrent nerves in either the chest or neck. We report our surgical experience of a case of esophagogastric anastomotic site recurrence occurring after Ivor Lewis operation with review of literatures.