Objectives : This study was to evaluate the effectiveness of Bee Venom acupuncture therapy on patients with cervical spondylosis. Methods: We investigated 29 cases of patients with cervical spondylosis. We divided patients into two groups: Bee venom Acupuncture was performed at one group, and the other group we did acupuncture therapy. To evaluate the effectiveness of treatment applied for two groups, we used visual analog scale(VAS) and neck disability index(NDI). We compared the VAS and NDI score of two groups statistically. Results : As a result of evaluation by using visual analog scale(VAS) and neck disability index(NDI), treatment score at final was significantly different from that at the baseline in each groups. Treatment at final, Bee venom acupuncture therapy group showed significant difference on visual analog scale(VAS) and neck disability index(NDI) compared with acupuncture therapy group. Conclusions : Bee Venom acupuncture therapy can be used with acupuncture therapy for highly effective in the patient with cervical spondylosis.