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길경(桔梗)의 추출조건에 따른 사포닌 함량의 변화
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  • 길경(桔梗)의 추출조건에 따른 사포닌 함량의 변화
  • Variation of Saponin Content in the Decoctions of Platycodi Radix
저자명
최재석,유대석,최연희,연규환,홍경식,이병회,김혜진,김현기,김은주,노성환,정영철,김영섭,유시용,Choi. Jae-Seok,Yoo. Dae-Seok,Choi. Yeon-Hee,Yon. Gyu-Hwan,Hong. Kyung-Sik,Le
간행물명
생약학회지
권/호정보
2007년|38권 2호|pp.128-132 (5 pages)
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한국생약학회
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정기간행물|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

We investigated the contents of crude saponin in the decoctions of Platycodi Radix prepared by the different extraction processes. Each lyophilized decoctions prepared by the different protocol were suspended in water and partitioned with ethylacetate (EtOAc) and n-butanol (BuOH), which gave the EtOAc fraction, BuOH fraction and the remaining water fraction, respectively. The content of crude saponin, which was estimated as the amount of BuOH fraction, and the HPLC profiles of the BuOH fraction were analyzed, and compared each others. The crude saponin content in the decoctions were increased proportionally to the increment of the extraction time, amount of water, extraction temperature and the number of repetition for extraction. Consequently, the optimized conditions were deduced to be suitable and recommendable for the preparation of Platycodi Radix ; the water amount needed for the extraction be 15-20 volumes to crude material, temperature for extraction be optimal at $85{sim}100^{circ}C$, extraction time be more than 5 hours and the repetition of extraction was 2 times.