Potential damage and losses associated with structural systems caused by earthquake can be reduced by application of seismic design to the structures. Because the building cost required for seismic design is generally higher than the cost for non-seismic design, the application of seismic design must be justified considering both seismic performance and cost. This paper presents a risk-based fiamework for evaluation and comparison of seismic performance of structures such that necessary data can be supplied for decision making on seismic design. Seismic fragility curve is utilized for seismic risk assessment of structures, and the process for decision analysis on adaptation of seismic design is presented based on the equivalent cost model.