This paper concerns with the application of e-based education methodology for people with disabilities targeting to empower them. Instead of the classic educational support such as extended time to take exams, a reader and/or scribe to assist with exams and note taking services, we suggest the use of new pedagogy-the science of educations integrating the state-of-the art. In this paper, we introduce the definition of disabilities for the people who does not fully understand what they means, first, and then possible implementing tools which can empower them with accomplishments. Most of the research in the field of pedagogy has tended to concentrate on the behavioral aspects of instructional sciences. Therefore we would like to point out that we concentrate on the aspects of instructional science particularly related with people with disabilities.