Purpose: This study is a descriptive survey to find out musculoskeletal symptoms in care workers working at medical welfare facilities for elders and factors affecting such symptoms. Methods: Data were collected from 115 care workers selected through convenient sampling from 6 medical welfare facilities in Seoul and Gyeonggi-do during the period from May 15th to May 19th. 2006. The Korean version of Job Content Questionnaire (JCQ) were used. Result: Of the subjects, 81.7% complained of musculoskeletal symptoms in two or more parts of their body. The frequency of body parts with musculoskeletal symptoms was high in order of shoulder, leg/foot, waist, neck/hand/wrist/finger and arm/elbow. The average job insecurity instability in the age group of 50-59 was 9.19, the average degree of regular exercise was 59.68. and the average job demand in those diagnosed with musculoskeletal diseases was 47.06, and the average job demand in those wounded during exercise or by an accident was 47.78, and all these were statistically significant. The heavier physical load in their work was, the higher their complaint of musculoskeletal symptoms was. In the lower social support group, the degree of complaint on musculoskeletal symptoms was remarkably high. Conclusion: The physical load of their duty and social support worked as the factors affecting musculoskeletal symptoms in care workers.