The lateral flow in the sub-channel of a nuclear rod bundle increase turbulent mixing and enhance heat transfer rate and safety. Various types of mixing vanes have been investigated to produce more lateral flow. In this study, the thermal-hydraulic characteristics of Hybrid mixing vane in a 17x17 rod bundle were calculated. Hybrid mixing vane has bended root part and split stem part. The computation was performed using a supercomputer due to the high number of grid meshes. The characteristics of Hybrid mixing vane were compared to Split mixing vane. The Hybrid mixing vane showed higher values of secondary intensity, cross-sectional turbulence intensity and Nu number and lower values of maximum temperature and standard deviation of temperature. Meanwhile, The Hybrid mixing vane has higher invariance because small vortexes travel, stretch and are connected with main stream.