Purpose: Since the 1990s, there has been an increasing interest in patient safety and quality of care. As a result, undergraduate nursing students have difficulties in clinical nursing practice such as health assessment or providing nursing skills. The purpose of this paper was to review current issues related to use of simulations in nursing education. Method: We conducted a thorough literature review including related proceedings to identify present issues in use of simulation education in nursing. Result/Conclusion: Simulation education in nursing differs from that in medical science. In nursing education, we need to focus on developing competencies for nursing students, for example, nursing process, nursing skills, and therapeutic communication skills With an increasing number of human patient simulators, we suggest a more careful approach including faculty development, curriculum development, and cost effective strategic planning. We propose a reliable and valid scenario development among nursing faculty as a consortium in the future.