The toxicity of seed extracts of three Indian medicinal plants, Azadirachta indica, Momordica charantia and Ricinus communis, was evaluated for their larvicidal efficacy against Anopheles stephensi. The methanol extract of A. indica exhibited potent larvicidal activity with $LC_{50}$ 15.25 and 12.70 ppm and $LC_{90}$ 46.79 and 45.56 ppm after 24 and 48 hrs, respectively, followed by methanol extract of R. communis with $LC_{50}$ 54.95 and 23.06 ppm and $LC_{90}$ 251.03 and 144.54 ppm after 24 and 48 hrs of post treatment, respectively. In case of M. charantia, the carbon tetrachloride extract possess potential larvicidal efficacy with $LC_{50}$ values 87.00 and 57.53 ppm and $LC_{90}$ 301.20 and 262.21 ppm after 24 and 48 hrs of exposure period. The results indicate that A. indica methanol extract was most potential mosquito larvicide and can be use as alternate potential to synthetic insecticides.