Dementia is a syndrome charaterized by a decline in multiple fields of cognitive domains. This is the case of a vascular dementia patient with disorientation, memory impairment and mental disorders. The patient was treated with herb medicine, Sesimtang mixed Gujuntang. As a result of herb medication, patient’s memory and disorientation were improved and the score of K-DRS(Korea-Dementia Rating Scale) and MMSE-K(Mini-Mental State Examination-K) was ascended.