Objectives : To discuss the biocompatibility of stainless steel for using acupuncture needles. Results and Conclusions : It is widely assumed that stainless steel is one of the good corrosion-resistant materials and is safe for human body, Most of metal acupuncture needles are made of STS304 and STS316 in light of human body safety: STS304 in more differences between STS304 and STS316 in light of human body safety: STS304 is more vulnerable to oxidation than STS316. A variety of literature survey showed that although STS316 is more corrosion-resistant than STS304 there is no evidence supporting the hypothesis that STS304 has the potential danger to human body, Further study would be necessary to draw more decisive conclusion.