In this paper, a hydropneumatic modeling and analysis of a heavy truck cabin air suspension system is presented. Cabin air suspension system is a system which improves ride comfort of a heavy truck and it can reduce vibration between truck frame and cabin. The components of the system, air spring, shock absorber, leveling valve and full cabin system are mathematically modelled using AMESim software. Simulation results of components and full cabin system are compared with experimental data of components and test results of a cabin using 6 axis simulation table. It is found that the simulation results are in good agreements with test results, and the hydropneumatic model can be used well to predict dynamic characteric of heavy truck cabin air suspension system.