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Haptoglobin SNP의 돼지 일당 증체량에 관한 효과
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  • Haptoglobin SNP의 돼지 일당 증체량에 관한 효과
  • Effects of SNPs in Haptoglobin on Average Daily Gain in Pig
저자명
김명직,정호영,조규호,전기준,김진형,Kim. Myung-Jick,Chung. Ho-Young,Cho. Kyu-Ho,Jeon. Gi-Jun,Kim. Jin-Hyung
간행물명
韓國受精卵移植學會誌
권/호정보
2008년|23권 3호|pp.197-201 (5 pages)
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한국수정란이식학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

In order to provide information of genetic variants for Haptoglobin (Hp) gene, which may be related to weight traits in pig, a total of 235 animals from National Institute of Animal Science (NIAS) were screened with 3 primers. The primer sequences were selected using the porcine cDNA sequences based on NM_214000, and the exon boundaries were estimated. Genetic variants were observed using direct sequencing analysis, and there were 9 SNPs detected at nucleotide positions 503 (A/G), 509 (A/G), 709 (C/T), 734 (C/A), 742 (G/A), 769 (A/G), 840 (C/T), 876 (C/T) and 882 (C/A). All the SNPs were located in coding regions, and mutations caused amino acid changes at nucleotide positions 503, 509, 734, 742 and 769. Allele frequencies of SNPs were estimated for all segments. The SNPs at nucleotide position 509 (p<0.0001) and 734 (p<0.05) were significantly associated with average daily gain, but no significance was observed with other SNPs. From the results, the identified SNPs may be a useful candidate marker for the porcine weight gain traits.