Experimental study has been performed to investigate the influence of non-condensible gas(NCG) charged mass on the thermal performance of a variable conductance heat pipe(VCHP) with screen mesh wick. The VCHP is furnished by screen mesh number 200 for the pipe outer diameter of 12.7mm and the pipe length of 500 mm. The VCHP is filled with water as working fluid of 4.8g and nitrogen as NCG and has evaporator, condenser and adiabatic section, respectively. For the results from experiment, it is found that, for the same charged mass of working fluid, the overall wall temperatures of heat pipe grows up with increasing NCG charged mass. The variation of operating temperature of VCHP reduces with increasing NCG mass. In addition, the profile of axial wall temperature distribution is presented for heat transport capacity of heat pipe, the temperature of cooling water of condenser, inclination angle, and operating temperature.