The thermal stress have an effect on the frictional factor such as applied load, sliding speed, sliding distance and number of ventilated disk hole. However, it is difficult to know the mutual relation of these factors on thermal stress of motorcycle break disk. For this, temperature of motorcycle break disk is measured using a disk-on-pad type friction tester with full factorial design containing above 4 elements. and the thermal stress analysis of it was carried out using with ANSYS workbench. From this study, the result was shown that the regression equation which have a trust rate of 95% for thermal stress presumption of motorcycle break disk with frictional factor was composed. It is possible to apply for another automobile parts.