Heat transfer from three-dimensional heat-generating modules was investigated. Simulated electronic module in an array configured with dummy module elements were used to measure the average heat transfer coefficients. Various module arrangements were tested using module spacings of 0.85 and 1.15 cm for six Reynolds numbers ranging from 500 to 975. The results show that a module placed in-line with and upstream of a heated module results in the heat transfer enhancement due to high turbulence intensity prompted by upstream modules. The highest enhancement occurs when the separation distance between modules is close to the module length in the flow direction. The laminar flow was observed on the front of the first module, slow recirculation regions on the sides parallel to the airstream, and turbulent flow on the back side. It appears that the first module serves to trip the air stream and produce a high level of turbulence, which enhances the heat transfer rate downstream.