- 유근피(楡根皮) 수추출물의 Helicobacter pylori에 대한 항균효과
- ㆍ 저자명
- 윤종현,이종화,김태헌,류영수,강형원,Yun. Jong-Hyun,Lee. Jong-Hwa,Kim. Tae-Heon,Lyu. Yeoung-Su,Kang. Hyung-Won
- ㆍ 간행물명
- 동의생리병리학회지
- ㆍ 권/호정보
- 2008년|22권 1호|pp.108-114 (7 pages)
- ㆍ 발행정보
- 대한동의생리학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
Present study was carried out for development of a new herb product with gastroprotective effect. Natural herbs mentioned that have gastrointenstial protective property in Donggeuibogam and reports were evaluated anti-bacterial activity against Helicobacter pylori, then Ulmus davidiana var. japonica Nakai (YGP) were selected. The material used for the test were water extract of Ulmus davidiana var. japonica Nakai. They were tested individually on HCl ethanol-induced gastric lesion in rats showed the most significant effectiveness, respectively. Then YGP was made, and tested on HCl ethanol, indomethacin-induced gastric lesion, shay ulcer and gastric secretion. Conclusions : YGP showed significant effect on HCl ethanol, indomethacin-induced gastric lesion, and Shay ulcer. It can be regarded that the antigastritic and anti-ulcerative effects of YGP is originated from reduction of total acid output identified by gastric secretion test.